BZAD-01, CAS 305339-41-7

Formulation: A solid

Formal Name: 4-(trifluoromethoxy)-N-[[2-(trifluoromethyl)phenyl]methyl]-benzenecarboximidamide

Purity: ≥98%

Formula Markup: C16H12F6N2O

Formula Weight: 362,3

Shelf life (days): 1460

CAS Number: 305339-41-7

Notes: BZAD-01 is an antagonist of NR2B subunit-containing NMDA receptors (Ki = 72 nM).{51579} It is selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits in a calcium mobilization assay (IC50s = 47 and >10,000 nM, respectively). Oral administration of BZAD-01 reduces hyperalgesia induced by carrageenan in rats (ED50 = 5.5 mg/kg). BZAD-01 (10 mg/kg) reduces dopaminergic neuron loss in the rat substantia nigra pars compacta and improves measures of ipsilateral curling, ipsilateral head positioning, and beam walking in a rat model of Parkinson’s disease induced by the catecholaminergic neurotoxin 6-OHDA (Item No. 25330).{51578}

• Artikelnummer: CAY38788-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38788-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK