Shelf life (days): 730
Info: An ionizable cationic lipid; has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo; LNPs containing lipid 35 selectively accumulate in the lungs, including in pulmonary epithelial, endothelial, myeloid, and dendritic cells, and spleen in mice; LNPs containing lipid 35 and encapsulating mRNA encoding Pseudomonas exotoxin A decrease the number of lung metastases and increase survival in a B16/F10.9 murine melanoma model
Formulation: A solution in methyl acetate
Formal Name: 11-(8-((2-hexyldecanoyl)oxy)octyl)-2-methyl-7-oxo-2,6,8,11-tetraazanonadecan-19-yl 2-hexyldecanoate, tetrahydrochloride
Purity: ≥95%
Formula Markup: C56H112N4O5 • 4HCl
Formula Weight: 960.985