Shelf life (days): 1460.0
Formulation: A solid
Formal Name: a-[2-[[3-(2,5-dihydro-2,5-dihydro-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethyl]-?-[[(10R)-7-hydroxy-7-oxido-2,13-dioxo-10-[(1-oxooctadecyl)oxy]-6,8,12-trioxa-3-aza-7-phosphatriacont-1-yl]oxy]-poly(oxy-1,2-ethanediyl)
Purity: ≥90%
Formula Markup: (C2H4O)nC52H94N3O13P
Formula Weight: 1058.365762
CAS Number: 569328-04-7
Notes: DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-rac-3-PE (DSPE). It has been used in the synthesis of lipid nanoparticles (LNPs) for the delivery of siRNA or small molecule anticancer agents in vitro and in vivo.{51868,63292,63293,62394} LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNAs targeting mRNA encoding p53 and K-RAS induce tumor regression in a PANC-1 pancreatic ductal adenocarcinoma mouse xenograft model.{51868}
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