Notes: Isodeoxycholic acid is a bile acid and an agonist of the farnesoid X receptor (FXR).{49954} It induces FXR-mediated gene expression in a reporter assay using COS-7 cells when used at a concentration of 30 µM. Isodeoxycholic acid also activates large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rabbit superior mesenteric arteries.{49955}