Shelf life (days): 1095.0
Formulation: A solution in ethanol
Formal Name: hexanedioic acid, 1,1'-[2-[4-(dimethylamino)-1-oxobutoxy]-1,3-propanediyl] 6,6'-bis(1-octylnonyl) ester
Purity: ≥95%
Formula Markup: C55H103NO10
Formula Weight: 938.426
CAS Number: 3028336-07-1
Notes: An ionizable cationic glycerolipid (pKa = 6.71); has been used in the generation of LNPs for the delivery of mRNA in vivo; LNPs containing lipid TG4C and encapsulating mRNA encoding human EPO increase serum EPO levels in mice; Nebulized administration of LNPs containing lipid TG4C and encapsulating mRNA encoding human HGF reduces BALF levels of Il-1β, Il-6, and Tnf-α in a mouse model of pulmonary emphysema induced by porcine pancreatic elastase