Mitoguazone, CAS 459-86-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2,2'-(1-methyl-1,2-ethanediylidene)bis-hydrazinecarboximidamide

Purity: ≥98%

Formula Markup: C5H12N8

Formula Weight: 184.2

CAS Number: 459-86-9

Notes: An inhibitor of SAMDC and DAO (IC50s = 1 and 0.33 µM for the rat and porcine enzymes, respectively); inhibits viral DNA integration and replication in HIV-1-infected primary human macrophages at 0.14 µM; decreases viability and induces mitochondrial swelling and cristae degradation in L1210 cells at 10 µM; reduces the proliferation of seven melanoma cancer cell lines (IC50s = 0.09-6.6 µM); decreases tumor weight in a PDX mouse model of differentiated papillary adenocarcinoma at 50 mg/kg per day in combination with DFMO

• Artikelnummer: CAY33803-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33803-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK