Product Description: 6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS)[1].
Applications: Cancer-programmed cell death
Formula: C18H14O5
References: [1]Hoshino T, et al. 6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis. Neurosci Res. 2021 Feb;163:43-51.
CAS Number: 16265-56-8
Molecular Weight: 310.30
Compound Purity: 98.0
Research Area: Cancer; Neurological Disease
Solubility: 10 mM in DMSO
Target: Reactive Oxygen Species