Product Description: Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor.Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C19H24O3
References: [1]Brooker L, et al. Carbon isotope ratio analysis of endogenous glucocorticoid urinary metabolites after cortisone acetate andadrenosterone administration for doping control. Drug Test Anal. 2012 Dec;4(12):951-61./[2]Choudhary MI, et al. Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. Steroids. 2007 Dec;72(14):923-9./[3]Joji Nakayama, et al. A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial-Mesenchymal Transition and Metastatic Dissemination. Mol Cancer Res. 2020 Mar;18(3):477-487.
CAS Number: 382-45-6
Molecular Weight: 300.39
Compound Purity: 98.97
Research Area: Cancer; Endocrinology
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: Androgen Receptor;Endogenous Metabolite
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