Product Description: (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action
Applications: Neuroscience-Neuromodulation
Formula: C21H24O5
References: [1]Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47./[2]Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.
CAS Number: 87402-88-8
Molecular Weight: 356.41
Compound Purity: 97.0
Research Area: Cardiovascular Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Calcium Channel
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