(−)-Gossypol (acetate), CAS 866541-93-7

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (2R)-1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde, compd. with acetic acid (1:1)

Purity: ≥98%

Formula Markup: C30H30O8 / C2H4O2

Formula Weight: 578.614

CAS Number: 866541-93-7

Notes: A polyphenol with spermicidal and anticancer activities; induces complete immobilization of isolated human sperm within 3 minutes at 5 mg/ml; inhibits Bcl-2, Bcl-xL, and Mcl-1 (Kis = 0.32, 0.48, and 0.18 µM, respectively); induces apoptosis in patient-derived B-CLL cells at 20 µM; induces tumor regression in an RL DLBCL mouse xenograft model at 35 mg/kg in combination with rituximab and cyclophosphamide

• Artikelnummer: CAY42421-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42421-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK