NecroX-7, CAS 1120332-55-9

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-(tetrahydro-2H-pyran-4-yl)-1H-indol-7-amine

Purity: ≥98%

Formula Markup: C24H29N3O3S

Formula Weight: 439.6

CAS Number: 1120332-55-9

Notes: A free radical scavenger and necrosis and ferroptosis inhibitor; scavenges DPPH and ABTS radicals in cell-free assays (EC50s = 2.6 and 11.96 µM, respectively); inhibits tBHP-induced necrosis in H9c2 cardiomyocytes and erastin-induced ferroptosis in HT-1080 cells (IC50s = 57 and 6 nM, respectively); reduces the activity of NOX by 53.3% in H9c2 lysates at 25 µM; prevents acetaminophen-induced decreases in cell viability and increases in ROS and RNS production in primary mouse hepatocytes at 25 µM; reduces doxorubicin-induced cardiomyopathy in rats at 100 mg/kg

• Artikelnummer: CAY42135-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42135-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK