Notes: Omidenepag isopropyl is a prodrug form of omidenepag (Item No. 41045), a non-prostaglandin agonist of the prostaglandin E2 (PGE2) receptor subtype EP2.{66941} It reduces intraocular pressure (IOP) in ocular normotensive and laser-induced ocular hypertensive cynomolgus monkeys when topically administered at a concentration of 0.01%/eye.{66941,69985} Formulations containing omidenepag isopropyl have been used in the treatment of open-angle glaucoma and ocular hypertension.