Oxatomide, CAS 60607-34-3

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-[3-[4-(diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one

Purity: ≥98%

Formula Markup: C27H30N4O

Formula Weight: 426.6

CAS Number: 60607-34-3

Notes: A histamine H1 receptor antagonist (Ki = 15 nM); selective for the histamine H1 receptor over mAChRs (Ki = 263 nM) but also inhibits 5-HT2 (Ki = 7 nM); inhibits histamine release induced by an anti-IgE antibody in isolated human lung fragments (IC50 = 4.5 nM); inhibits A23187-induced degranulation of RBL-2H3 mast cells; inhibits LPS-induced NO production in RAW 264.7 cells at 50 µM and fMLP- or PMA-induced superoxide production in isolated rat neutrophils; reduces histamine-induced vascular permeability in mice (ED50 = 2.9 mg/kg)

• Artikelnummer: CAY42288-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 42288-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK