Adatanserin, CAS 127266-56-2

Product Description: Adatanserin (WY-50324) is a high affinity, selective and partial agonist for the 5-HT1A receptor with a Ki of 1 nM. Adatanserin is a moderate affinity 5-HT2 receptor antagonist with a Ki of 73 nM. Adatanserin shows significant anxiolytic and antidepressant activity in an animal conflict model[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C21H31N5O

References: [1]M A Abou-Gharbia, et al. Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents. /[2]A Singh, et al. Antidepressant-like activity of compounds with varying efficacy at 5-HT1A receptors. Neuropharmacology. 1993 Apr;32(4):331-40.

CAS Number: 127266-56-2

Molecular Weight: 369.50

Research Area: Neurological Disease

Target: 5-HT Receptor

• Artikelnummer: MEXHY-121053-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-121053-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK