Product Description: NO-Losartan A (compound 2a) displays vasorelaxing effects, due to the release of NO, and antagonized the vasocontractile effects of Angiotensin II (HY-13948), with potency values similar to that of Losartan (HY-17512)[1].
Applications: Neuroscience-Neuromodulation
Formula: C30H28ClN7O5
References: [1]Maria C Breschi, et al. NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs. J Med Chem. 2004 Nov 4;47(23):5597-600.
CAS Number: 791122-48-0
Molecular Weight: 602.04
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Angiotensin Receptor