Product Description: Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).
Applications: Neuroscience-Neuromodulation
Formula: C110H192N40O24S4
References: [1]Hanson JM, et al. Anti-inflammatory property of 401 (MCD-peptide), a peptide from the venom of the bee Apis mellifera (L.). Br J Pharmacol. 1974 Mar;50(3):383-92./[2]Banks BE, et al. Anti-inflammatory activity of bee venom peptide 401 (mast cell degranulating peptide) andcompound 48/80 results from mast cell degranulation in vivo. Br J Pharmacol. 1990 Feb;99(2):350-4.
CAS Number: 32908-73-9
Molecular Weight: 2587.22
Compound Purity: 98.26
Research Area: Inflammation/Immunology; Endocrinology
Solubility: H2O : 2.08 mg/mL (ultrasonic)
Target: 5-HT Receptor;Histamine Receptor
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