Product Description: Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID) and an inhibitor of calcium sensing receptor (CaSR). unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent[1].
Applications: COVID-19-immunoregulation
Formula: C18H18N2O
References: [1]Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID). unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent<sup>[1]</sup>./[2]Shntaif A H, et al. Quantum chemical calculations on two compounds of proquazone and proquazone type calcites as a calcium sensing receptor (CaSR) inhibitory profiles[J]. Russian Journal of Bioorganic Chemistry, 2021, 47(3): 777-783.
CAS Number: 22760-18-5
Molecular Weight: 278.35
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: CaSR
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