Product Description: (Rac)-SAR131675 is the racemate of SAR131675. SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C18H22N4O4
References: [1]Mitroshina EV, et al. Neuroprotective Effect of Kinase Inhibition in Ischemic Factor Modeling In Vitro. Int J Mol Sci. 2021;22(4):1885./[2]Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49.
CAS Number: 1092539-44-0
Molecular Weight: 358.39
Compound Purity: 98.0
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: VEGFR