Product Description: N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies[1][2][3].
Formula: C8H9NO5S
References: [1]J.L.M.Heeremans, et al. Interference of ϵ-amino-caproic acid with [N-succinimidyl S-acetylthioacetate derived] thiol-introduction into glu-plasminogen. Volume 8, Supplement 2, 1994, Pages 138-141./[2]Allen KJH, et al. Evaluation of N-Succinimidyl S-Acetylthioacetate Ligand for Radiolabeling of HumanizedAntibodies with 188Rhenium. Cancer Biother Radiopharm. 2018 Oct;33(8):349-355./[3]Nanda S, et al. Thermostable alpha-amylase conjugated antibodies as probes for immunodetection in ELISA. J Immunoassay Immunochem. 2002;23(3):327-45.
CAS Number: 76931-93-6
Molecular Weight: 231.23
Compound Purity: 99.56
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Biochemical Assay Reagents
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