Product Description: SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research[1].
Applications: Cancer-programmed cell death
Formula: C48H84NO8P
References: [1]Yuanyuan Liu, et al. DHA-enriched phosphatidylcholine suppressed angiogenesis by activating PPARγ and modulating the VEGFR2/Ras/ERK pathway in human umbilical vein endothelial cells. Food Sci Biotechnol. 2021 Oct 27;30(12):1543-1553.
CAS Number: 59403-52-0
Molecular Weight: 834.16
Research Area: Cancer; Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: PPAR
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