Product Description: Trehalose 6,6'-dimycolate (Cord Factor) is trehalose 6,6'-dimycolate, a cell wall glycolipid of Mycobacterium tuberculosis, which can be used to simulate inflammation and granuloma induced by Mycobacterium tuberculosis (MTB) form. Trehalose 6,6′-dimycolate also protects Mycobacterium tuberculosis from macrophage-mediated killing, inhibits efficient antigen presentation, and reduces the development of protective T cell responses[1][2].
Formula: N/A
References: [1]Hwang SA, et al. Mycobacterial trehalose 6,6'-dimycolate induced vascular occlusion is accompanied by subendothelial inflammation. Tuberculosis (Edinb). 2019 May;116S:S118-S122./[2]Welsh KJ, et al. Trehalose 6,6'-dimycolate--a coat to regulate tuberculosis immunopathogenesis. Tuberculosis (Edinb). 2013 Dec;93 Suppl:S3-9.
CAS Number: 61512-20-7
Molecular Weight: N/A
Compound Purity: 98.0
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Biochemical Assay Reagents
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