Product Description: Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury[1].
Formula: N/A
References: [1]Du J, et al. Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2. Cell Death Dis. 2022 Oct 20;13(10):884. /[2]Monroe LL, et al. Zymosan-Induced Peritonitis: Effects on Cardiac Function, Temperature Regulation, Translocation of Bacteria, and Role of Dectin-1. Shock. 2016 Dec;46(6):723-730.
CAS Number: 58856-93-2
Molecular Weight: N/A
Research Area: Inflammation/Immunology; Others
Solubility: DMSO : 1.94 mg/mL (ultrasonic;warming;adjust pH to 4 with HCl;heat to 60°C)
Target: Toll-like Receptor (TLR)