Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2-(1-piperazinyl)-quinoline, (2Z)-2-butenedioate (1:2)
Purity: ≥98%
Formula Markup: C13H15N3 / 2C4H4O4
Formula Weight: 445.4
CAS Number: 150323-78-7
Notes: A 5-HT2A, 5-HT2B, and 5-HT2C receptor agonist; induces calcium accumulation in CHO-K1 cells expressing 5-HT2A, 5-HT2B, or 5-HT2C receptors (EC50s = 309.03, 177.83, and 338.84 nM, respectively, for the human receptors); binds to the 5-HT3 receptor (Ki = 2.1 nM); decreases food intake in rats at 2.5, 5, or 10 mg/kg; restores spinal circuitry function, improves gait regularity, and increases interlimb coordination and limb weight-bearing in a rat model of spinal cord transection-induced hindlimb paralysis at 0.3 mg/kg per day in combination with 8-hydroxy DPAT, electrode stimulation of dorsal and lumbar spine regions, and locomotor training
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