Product Description: 16-epi-latrunculin B is anticancer agent, which can inhibit the growth of HeLa cells with IC50 value of 3.9 uM[1]. 16-epi-latrunculin B has antiviral activity against HSV-1 (ED50 of 1 µg/mL)[2].
Applications: Cancer-programmed cell death
Formula: C20H29NO5S
References: [1]Diaa T A Youssef, et al. Magnificines A and B, Antimicrobial Marine Alkaloids Featuring a Tetrahydrooxazolo[3,2-a]azepine-2,5( 3H,6H)-dione Backbone from the Red Sea Sponge <i>Negombata magnifica</i>. Mar Drugs. 2021 Apr 12;19(4):214./[2]Thomas R Hoye, et al. Toward computing relative configurations: 16-epi-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B. J Am Chem Soc. 2002 Jun 26;124(25):7405-10.
CAS Number: 444911-05-1
Molecular Weight: 395.51
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: HSV
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