A09-003, CAS 2911646-14-3

A09-003, CAS 2911646-14-3
Artikelnummer
MEXHY-155245-1
Verpackungseinheit
1 mg
Hersteller
MedChemExpress

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Product Description: A09-003 is a CDK-9 inhibitor (IC50: 16 nM). A09-003 inhibits leukemia cell proliferation (IC50: 1.90, 0.86, 2.49, 1.84, 0.48 μM for BDCM, Molm-14, THP-1, U937, MV4-11 cells). A09-003 induces apoptosis and decreases Mcl-1 expression through Thr163 dephosphorylation[1].

Applications: Cancer-Kinase/protease

Formula: C23H26N4O

References: [1]Sim KM, et al. A new cyclin-dependent kinase-9 inhibitor A09-003 induces apoptosis in acute myeloid leukemia cells with reduction of myeloid cell leukemia sequence-1 protein. Chem Biol Interact. 2023 Sep 1;382:110554.

CAS Number: 2911646-14-3

Molecular Weight: 374.48

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Bcl-2 Family;CDK
Mehr Informationen
Artikelnummer MEXHY-155245-1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-155245-1
Verpackungseinheit 1 mg
Mengeneinheit STK
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