Product Description: Anticancer agent 264 (Compound 5w) is an anticancer agent that exhibits significant antiproliferative activity across tumor cell lines, with an IC50 range of 7.5-33.67 μM.Anticancer agent 264 significantly induces G2/M phase arrest in MDA-MB-231, MIA PaCa-2, and DU-145 cell lines.Anticancer agent 264 reduces the expression of key cell cycle proteins, including CDK1, CDK2, and Cyclin B1, in a dose-dependent manner, and shows strong binding affinity with inhibitor of differentiation (ID) proteins and DNA-binding proteins.Anticancer agent 264 can be used for research in the field of cancer-related diseases[1].
Formula: C23H18ClF5N6O
References: [1]Nagineni D, et al. Imidazole-1,2,4-oxadiazole-piperazine hybrids as potent anticancer agents: Synthesis, biological evaluation and molecular docking. Bioorg Chem. 2025 Mar;156:108208.
Molecular Weight: 524.87
Research Area: Cancer
Target: CDK;DNA/RNA Synthesis
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