Antidepressant agent 9, CAS 143899-90-5

Antidepressant agent 9, CAS 143899-90-5
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MEXHY-170945-0
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Product Description: Antidepressant agent 9 (Compound 24) is an orally active and BBB-penetrable NMDAR and SERT inhibitor with IC50 values of 3.50 μM and 1044 nM, respectively. Antidepressant agent 9 has good metabolic stability and plasma exposure. Antidepressant agent 9 can exert antidepressant-like activity in the mouse forced swim test[1].

Applications: Neuroscience-Neurodegeneration

Formula: C17H24N2

References: [1]Ji J, et al. D-morphinan analogs with favorable pharmacokinetic profiles as dual-acting antidepressants. Eur J Med Chem. 2025 Apr 5;287:117349.

CAS Number: 143899-90-5

Molecular Weight: 256.39

Research Area: Neurological Disease

Target: iGluR;Serotonin Transporter
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Artikelnummer MEXHY-170945-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-170945-0
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