Product Description: BI-7273 is a selective, and cell-permeable BRD9 inhibitor, with an IC50 and a Kd of 19 and 0.75 nM; also shows high effect on BRD7, with an IC50 and a Kd of 117 nM and 0.3 nM.
Applications: Cancer-Kinase/protease
Formula: C20H23N3O3
References: [1]Martin LJ, et al. Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem. 2016 May 26;59(10):4462-75./[2]Laetitia J Martin, et al. Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem. 2016 May 26;59(10):4462-75.
CAS Number: 1883429-21-7
Molecular Weight: 353.41
Compound Purity: 99.83
Research Area: Cancer
Solubility: DMSO : 10 mg/mL (ultrasonic)
Target: Epigenetic Reader Domain