BRD4 degrader-1

Product Description: BRD4 degrader-1 (Compound ML 1-50) is a monovalent and covalent molecular glue BRD4 degrader. BRD4 degrader-1 targets DCAF16 (E3 ligase) and degrades both the long and short isoforms of BRD4 in cells[1].

Applications: Cancer-programmed cell death

Formula: C25H27ClN6O3S2

References: [1]Melissa Lim, et al. DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders.ACS Central Science. DOI: 10.1021/acscentsci.4c00286

Molecular Weight: 559.10

Compound Purity: 99.85

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: E1/E2/E3 Enzyme;Epigenetic Reader Domain;Molecular Glues

• Artikelnummer: MEXHY-163638-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163638-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK