C12-Ceramide (Standard), CAS 74713-60-3

C12-Ceramide (Standard), CAS 74713-60-3
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MEXHY-100353R-0
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MedChemExpress

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Product Description: C12-Ceramide (Standard) is the analytical standard of C12-Ceramide. This product is intended for research and analytical applications. C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease[1][1].

Formula: C30H59NO3

References: [1]He X, et, al. A fluorescence-based, high-performance liquid chromatographic assay to determine acid sphingomyelinase activity and diagnose types A and B Niemann-Pick disease. Anal Biochem. 2003 Mar 1;314(1):116-20./[2]Øverbye A, et, al. Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide. Oncotarget. 2017 Aug 12;8(44):76921-76934.

CAS Number: 74713-60-3

Molecular Weight: 481.79

Research Area: Cancer; Metabolic Disease

Target: Others;Reference Standards
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Artikelnummer MEXHY-100353R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-100353R-0
Verpackungseinheit Get quote
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