Product Description: CDK2 degrader 5 (compound 12) is a degrader for CDK2, with the Dmax of >50% and ≤80% in HiBiT Assay. CDK2 degrader 5 plays an important role in cancer research[1].
Applications: Cancer-Kinase/protease
Formula: C29H27N3O5
References: [1]Monte Rosa Therapeutics, Inc. Preparation of 3-(6-substituted-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives that mediate the degradation of cyclin-dependent kinase (CDK2) and are useful in the treatment of various disorders, such as cancer. World Intellectual Property Organization, WO2023069700 A1 2023-04-27
CAS Number: 2923574-11-0
Molecular Weight: 497.54
Compound Purity: 99.17
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: CDK