Desmethyl Bosentan, CAS 253688-61-8

Product Description: Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan (HY-A0013).1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.

Applications: Metabolism-protein/nucleotide metabolism

Formula: C26H27N5O6S

References: [1]van Giersbergen, et al. Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptor. Br. J. Clin. Pharmacol. 54(5), 561-562 (2002).

CAS Number: 253688-61-8

Molecular Weight: 537.59

Research Area: Metabolic Disease

Target: Cytochrome P450;Drug Metabolite

• Artikelnummer: MEXHY-145516-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-145516-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK