DH-376, CAS 1848233-57-7

Product Description: DH-376 is a potent diacylglycerol lipase inhibitor with pIC50 values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice[1]. DH-376 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Metabolism-sugar/lipid metabolism

Formula: C31H28F2N4O3

References: [1]Deng H, et, al. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017 Jan 12;60(1):428-440.

CAS Number: 1848233-57-7

Molecular Weight: 542.58

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: DAGL;MAGL

• Artikelnummer: MEXHY-120171-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-120171-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK