DXR-IN-4

Product Description: DXR-IN-4 (Compound 12a) is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC50s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC50 of 11 μM and 12 μM[1].

Formula: C16H26NO6PS

References: [1]Knak T, et al., Expanding the Chemical Space of Reverse Fosmidomycin Analogs. ACS Med Chem Lett. 2024 Dec 23;16(1):136-143.

Molecular Weight: 391.42

Research Area: Infection

Target: Parasite

• Artikelnummer: MEXHY-170783-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170783-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK