E3 ligase Ligand 48

Product Description: E3 ligase Ligand 48 is a CRBN ligand for PROTAC AR Degrader-9 (HY-170448). PROTAC AR Degrader-9 (Compound c6) is a PROTAC degrader for androgen receptor, that degrades AR in human hair follicle papilla cells (HDPCs) with a DC50 of 262.38 nM[1].

Formula: C18H21N3O4

References: [1]Xinfei Mao, et al. Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia. J Med Chem. 2024 Dec 26;67(24):22218-22244.

Molecular Weight: 343.38

Research Area: Others

Target: Ligands for E3 Ligase

• Artikelnummer: MEXHY-170449-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170449-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK