eIF4E-IN-4, CAS 1373822-39-9

eIF4E-IN-4, CAS 1373822-39-9
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MEXHY-148664-0
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MedChemExpress

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Product Description: eIF4E-IN-4 (Compound 33) is a selective inhibitor of eukaryotic initiation factor 4E (eIF4E) with biochemicalactivity value of 95 nM. eIF4E-IN-4 inhibits cap-dependent mRNA translation with an IC50 value of 2.5 μM. eIF4E-IN-4 can be used for breast cancer, colon cancer, and head and neck cancer study[1].

Applications: Cancer-programmed cell death

Formula: C20H19ClN5O5P

References: [1]Chen X, et al. Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction. J Med Chem. 2012 Apr 26;55(8):3837-51.

CAS Number: 1373822-39-9

Molecular Weight: 475.82

Research Area: Cancer

Target: Eukaryotic Initiation Factor (eIF)
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Artikelnummer MEXHY-148664-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-148664-0
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