Product Description: G-quadruplex ligand 3 (Compound 16) is a G-quadruplex ligand with anticancer effects that chelate iron. G-quadruplex ligand 3 stabilizes G-quadruplexes in human leukemia Jurkat cells. G-quadruplex ligand 3 localizes in the cell nucleus, serving as a fluorescent nuclear tracer for the labile iron pool[1].
Formula: C18H20N4O4
References: [1]Piccolo M, et al. Design, Synthesis, and Anticancer Activity of Drug-like Iron Chelators/G-Quadruplex Binders as Synergic Dual Targeting Agents. J Med Chem. 2025 Jan 23;68(2):1245-1259.
Molecular Weight: 356.38
Research Area: Cancer
Target: G-quadruplex