GDC-0134, CAS 1637394-01-4

GDC-0134, CAS 1637394-01-4
Artikelnummer
MEXHY-148629-10.1
Verpackungseinheit
10 mM/1 ml
Hersteller
MedChemExpress

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Product Description: GDC-0134 is a potent, selective, orally active, brain-penetrant dual leucine zipper kinase (DLK) inhibitor. GDC-0134 blocks DLK activity in cellular assays and in animal models of neuronal injury. GDC-0134 can be used for the study of amyotrophic lateral sclerosis (ALS)[1].

Applications: Neuroscience-Neurodegeneration

Formula: C19H20F4N6O2

References: [1]Jonathan S Katz, et al. A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS. Ann Clin Transl Neurol. 2022 Jan;9(1):50-66.

CAS Number: 1637394-01-4

Molecular Weight: 440.39

Compound Purity: 99.18

Research Area: Neurological Disease

Target: JNK
Mehr Informationen
Artikelnummer MEXHY-148629-10.1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-148629-10.1
Verpackungseinheit 10 mM/1 ml
Mengeneinheit STK
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