H3B-8800, CAS 1825302-42-8

H3B-8800, CAS 1825302-42-8
Artikelnummer
MEXHY-111517-100
Verpackungseinheit
100 mg
Hersteller
MedChemExpress

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Product Description: H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].

Applications: Cancer-programmed cell death

Formula: C31H45N3O6

References: [1]Seiler M, et al. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nat Med. 2018 May;24(4):497-504.

CAS Number: 1825302-42-8

Molecular Weight: 555.71

Compound Purity: 98.85

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Apoptosis;SF3B1
Mehr Informationen
Artikelnummer MEXHY-111517-100
Hersteller MedChemExpress
Hersteller Artikelnummer HY-111517-100
Verpackungseinheit 100 mg
Mengeneinheit STK
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