HD-TAC7, CAS 2978763-95-8

Product Description: HD-TAC7 is a potent PROTAC HDAC degrader with IC50 values of 3.6 μM, 4.2 μM and 1.1 μM for HDAC1, HDAC2 and HDAC3, respectively. HD-TAC7 can decreases NF-κB p65 in RAW 264.7 macrophages. HD-TAC7 can be used for the research of inflammatory diseases like asthma and chronic obstructive pulmonary disease (COPD)[1].

Applications: COVID-19-immunoregulation

Formula: C33H32FN7O7

References: [1]Fangyuan Cao, et al. Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC). Eur J Med Chem. 2020 Dec 15;208:112800.

CAS Number: 2978763-95-8

Molecular Weight: 657.65

Compound Purity: 98.75

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: HDAC;PROTACs

• Artikelnummer: MEXHY-146346-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-146346-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK