HDAC1-IN-8, CAS 3066143-73-2

Product Description: HDAC1-IN-8 (compound 5c) is a potent and selective HDAC1 inhibitor with IC50 values of 11.94, 22.95, >500 µM for HDAC1, HDAC6, HDAC8, respectively. HDAC1-IN-8 shows antiproliferative activity. HDAC1-IN-8 induces cell cycle arrest at G1 and G2/M. HDAC1-IN-8 induces autophagy. HDAC1-IN-8 shows anticancer activity and has the potential for the research of lung cancer[1].

Formula: C22H24N2O4

References: [1]Joshi G, et al. Design and Synthesis of Topoisomerases-Histone Deacetylase Dual Targeted Quinoline-Bridged Hydroxamates as Anticancer Agents. J Med Chem. 2025 Jan 14.

CAS Number: 3066143-73-2

Molecular Weight: 380.44

Research Area: Cancer

Target: Autophagy;HDAC

• Artikelnummer: MEXHY-168477-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-168477-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK