Product Description: HNC-1664 is the orally active inhibitor for RNA-dependent RNA polymerase (RdRP). HNC-1664 exhibits broad-spectrum antiviral activity against coronavirus (SARS-CoV-2 wildtype and its mutants XBB.1.18, HK.3.1, BF.7.14, BA.1HCoV-229E, HCoV-OC43) and arenavirus. HNC-1664 exhibits anti-infectious activity in SARS-CoV-2 Delta infected mouse models[1].
Formula: C12H13FIN3O3
References: [1]Jia X, et al., An adenosine analog shows high antiviral potency against coronavirus and arenavirus mainly through an unusual base pairing mode. Nat Commun. 2024 Dec 30;15(1):10750.
CAS Number: 2127358-36-3
Molecular Weight: 393.15
Research Area: Infection
Target: Arenavirus;DNA/RNA Synthesis;SARS-CoV