HRG038

Product Description: HRG038 is a selective covalent BRD4 degrader. HRG038 binds covalently to the E3 ubiquitin ligase CUL4 DCAF16, recruiting it to BRD4, leading to the ubiquitination and subsequent proteasomal degradation of BRD4. HRG038 is promising for research of cancers[1].

Formula: C34H31Cl2N11O3S

References: [1]Lauren M Orr, et al. DCAF16-Based Covalent Degradative Handles for the Modular Design of Degraders. Biorxiv, April 25, 2025.

Molecular Weight: 744.65

Research Area: Cancer

Target: Epigenetic Reader Domain

• Artikelnummer: MEXHY-176070-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-176070-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK