HuR degrader 2, CAS 3040301-46-7

Product Description: HuR degrader 2 (Compound 3) is a molecule glue, which targets RNA-binding protein Hu antigen R (HuR) and degrades 30% HuR at 0.1 μM. HuR degrader 2 inhibits the proliferation of cancer cell Colo-205, with IC50≤200 nM. HuR degrader 2 exhibits a high affinity with cereblon, with an HTRF ratio [1].

Applications: Cancer-programmed cell death

Formula: C20H15N3O3

References: [1]Zou L, et al., Compounds for modulating hur (elavl1). WO2024114639.

CAS Number: 3040301-46-7

Molecular Weight: 345.35

Compound Purity: 98.47

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HuR;Molecular Glues

• Artikelnummer: MEXHY-163759-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163759-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK