HZS60, CAS 3027529-88-7

Product Description: HZS60 is a NMDAR/TRPM4 inhibitor with brain permeability that can improve cerebral ischemia. HZS60 has significant neuroprotective effects on primary neuronal ischemic damage caused by NMDA and oxygen-glucose deprivation/reoxygenation. HZS60 exhibits good pharmacokinetic characteristics and can inhibit cerebral ischemia-reperfusion injury. HZS60 can be used as a potential inhibitor of ischemic stroke[1].

Applications: Neuroscience-Neuromodulation

Formula: C13H17F2N3

References: [1]Sun M, et al. Discovery of HZS60 as a Novel Brain Penetrant NMDAR/TRPM4 Interaction Interface Inhibitor with Improved Activity and Pharmacokinetic Properties for the Treatment of Cerebral Ischemia. J Med Chem. 2025 Jan 23;68(2):2008-2043.

CAS Number: 3027529-88-7

Molecular Weight: 253.29

Research Area: Neurological Disease

Target: TRP Channel

• Artikelnummer: MEXHY-170790-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170790-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK