JET-209, CAS 3033714-58-5

Product Description: JET-209 is a potent PROTAC CBP/p300 degrader, with DC50 values of 0.05 nM and 0.2 nM for CBP and p300. JET-209 contains Lenalidomide (HY-A0003) (the cereblon ligand), a linker and GNE-207 (HY-120028) (bromodomain Inhibitor). JET-209 is used for cancer research[1].

Applications: Cancer-programmed cell death

Formula: C46H47N9O6

References: [1]Thomas JE 2nd, et al. Discovery of Exceptionally Potent, Selective, and Efficacious PROTAC Degraders of CBP and p300 Proteins. J Med Chem. 2023 Jun 22;66(12):8178-8199.

CAS Number: 3033714-58-5

Molecular Weight: 821.92

Compound Purity: 98.09

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Histone Acetyltransferase;PROTACs

• Artikelnummer: MEXHY-154984-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-154984-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK