JPS036, CAS 2669785-85-5

JPS036, CAS 2669785-85-5
Artikelnummer
MEXHY-145819-5
Verpackungseinheit
5 mg
Hersteller
MedChemExpress

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Product Description: JPS036 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS036 degrades class I histone deacetylase (HDAC). JPS036 is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1].

Applications: Cancer-programmed cell death

Formula: C51H66FN7O7S

References: [1]Smalley JP, et al. Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells. J Med Chem. 2022;65(7):5642-5659.

CAS Number: 2669785-85-5

Molecular Weight: 940.18

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: HDAC;PROTACs
Mehr Informationen
Artikelnummer MEXHY-145819-5
Hersteller MedChemExpress
Hersteller Artikelnummer HY-145819-5
Verpackungseinheit 5 mg
Mengeneinheit STK
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