Product Description: JYQ-173 is a selective inhibitor for human Parkinson disease protein 7 (PARK7), with an IC50 of 19 nM. JYQ-173 exhibits good cell permeability. JYQ-173 is the ligand for target protein PARK7, which can be utilized for synthesis of PROTAC Degrader JYQ-194 (HY-163564)[1].
Applications: Neuroscience-Neurodegeneration
Formula: C21H19FN8O2S
References: [1]Jia Y, et al., Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell. J Med Chem. 2024 May 23;67(10):7935-7953.
Molecular Weight: 466.49
Research Area: Neurological Disease
Target: Ligands for Target Protein for PROTAC