KIF2C-IN-1

KIF2C-IN-1
Artikelnummer
MEXHY-173522-0
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MedChemExpress

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Product Description: KIF2C-IN-1 (Compound 7S9) is a selective and potent small-molecule KIF2C inhibitor. KIF2C-IN-1 stabilizes the KIF2C-tubulin interaction, blocking the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel (HY-B0015) in paclitaxel-resistant triple-negative breast cancer (TNBC) cells and significantly reduces tumor growth combined with Paclitaxel in mouse models[1].

Formula: C36H39ClN4O9S

References: [1]Pao YS, et al. KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules. Dev Cell. 2025 Mar 25:S1534-5807(25)00151-0.

Molecular Weight: 739.23

Research Area: Cancer

Target: Kinesin
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Artikelnummer MEXHY-173522-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-173522-0
Verpackungseinheit Get quote
Mengeneinheit STK
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