Lenacapavir, CAS 2189684-44-2

Product Description: Lenacapavir (GS-6207) is a HIV-1 capsid inhibitor. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs)[1]. Lenacapavir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: COVID-19-anti-virus

Formula: C39H32ClF10N7O5S2

References: [1]Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019 Jun 20;10:1227./[2]John O Link, et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature. 2020 Jul 1.

CAS Number: 2189684-44-2

Molecular Weight: 968.28

Compound Purity: 98.44

Research Area: Infection

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: HIV

• Artikelnummer: MEXHY-111964-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-111964-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK